Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3180576 | 0.98 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1SMN1; SMN2MAPK1MAPT | |
| SCHEMBL3180569 | 0.83 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL13784463 | 0.83 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL1335837 | 0.81 | L3MBTL1 (0.60) | L3MBTL1ALDH1A1SMN1; SMN2MAPK1MAPT | |
| SCHEMBL3981132 | 0.81 | KDM4E (0.43) | L3MBTL1ALDH1A1SMN1; SMN2MAPK1MAPT | |
| SCHEMBL30984209 | 0.81 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1SMN1; SMN2MAPK1MAPT | |
| SCHEMBL20709966 | 0.79 | KDM4E (0.36) | L3MBTL1ALDH1A1SMN1; SMN2MAPK1MAPT | |
| Hydrochloric Acid SCHEMBL8760435 | 0.79 | L3MBTL1 (0.58) | L3MBTL1ALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL20709965 | 0.79 | L3MBTL1 (0.42) | L3MBTL1ALDH1A1SMN1; SMN2MAPK1MAPT | |
| SCHEMBL20027637 | 0.79 | L3MBTL1 (0.42) | L3MBTL1ALDH1A1SMN1; SMN2MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350176-B1 | Method for preparing pyrazolecarboxylic acid and derivatives | NISSAN CHEMICAL IND LTD (JP) | 1995-08-30 | — | — | EP | claimed |
| EP-0350176-A2 | Method for preparing pyrazolecarboxylic acid and derivatives | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1990-01-10 | — | — | EP | claimed |
| JP-7304747-A | — | — | None | — | — | JP | disclosed |
| US-20230167094-A1 | H4 ANTAGONIST COMPOUNDS | HEPTARES THERAPEUTICS LIMITED (GB) | 2023-06-01 | — | — | US | disclosed |
| US-11339130-B1 | Calpain modulators and therapeutic uses thereof | BLADE THERAPEUTICS, INC. (US) | 2022-05-24 | — | — | US | disclosed |
| US-10934261-B2 | Calpain modulators and therapeutic uses thereof | BLADE THERAPEUTICS, INC. (US) | 2021-03-02 | — | — | US | disclosed |
| US-10894776-B2 | — | — | 2021-01-19 | — | — | US | disclosed |
| CN-1058490-C | Tetrazolinone derivatives | BAYER AGROCHEM KK (JP) | 2000-11-15 | — | — | CN | disclosed |
| EP-0695748-B1 | Tetrazolinone herbicides | BAYER AGROCHEM KK (JP) | 1999-05-06 | — | — | EP | disclosed |
| US-5589439-A | HERBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 1996-12-31 | — | — | US | disclosed |
| US-5545608-A | EFFECTIVE AGAINST PADDY WEEDS WHILE SAFE FOR RICE PLANTS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1996-08-13 | — | — | US | disclosed |
| EP-0695748-A1 | Tetrazolinone herbicides | NIHON BAYER AGROCHEM K.K. (JP) | 1996-02-07 | — | — | EP | disclosed |
| JP-H07304747-A | 3,5-DICHLORO-4-CYANO-1-METHYLPYRAZOLE AND PRODUCTION THEREOF | NISSAN CHEM IND LTD | 1995-11-21 | — | — | JP | disclosed |
| EP-0350176-B1 | Method for preparing pyrazolecarboxylic acid and derivatives | NISSAN CHEMICAL IND LTD (JP) | 1995-08-30 | — | — | EP | disclosed |
| EP-0638555-A1 | PYRAZOLEGLYCOLAMIDE DERIVATIVE | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1995-02-15 | — | — | EP | disclosed |
| US-5202442-A | Process for preparing pyrazolecarboxylic acid compounds | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| US-5053517-A | PROCESS FOR PREPARING PYRAZOLECARBOXYLIC ACID COMPOUNDS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1991-10-01 | — | — | US | disclosed |
| EP-0350176-A2 | Method for preparing pyrazolecarboxylic acid and derivatives | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1990-01-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10934261-B2 | Calpain modulators and therapeutic uses thereof | CAPNS1, CAPN9, CAPN1 | L3MBTL1 3522/4885ALDH1A1 4193/4885SMN1; SMN2 200/4885 |
| US-10894776-B2 | — | CAPNS1, CAPN9, CAPN2 | L3MBTL1 4453/4885ALDH1A1 4421/4885SMN1; SMN2 263/4885 |
| US-11339130-B1 | Calpain modulators and therapeutic uses thereof | CAPNS1, CAPN9, CAPN1 | L3MBTL1 3522/4885ALDH1A1 4193/4885SMN1; SMN2 200/4885 |
| US-20230167094-A1 | H4 ANTAGONIST COMPOUNDS | HRH4, HRH3, HRH2 | L3MBTL1 2259/4885ALDH1A1 3149/4885SMN1; SMN2 3911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.