Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | ABL1 | P00519 | 3/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.50 |
| ▸ | BCR | P11274 | 3/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17514699 | 0.83 | CYP1A1 (0.50) | ABL1ABCB1BCRHSD17B1HSD17B2 | |
| SCHEMBL920933 | 0.79 | ABL1 (0.71) | NPC1RAB9ASMN1; SMN2TP53MAPK1 | |
| SCHEMBL3743494 | 0.79 | ABL1 (0.71) | NPC1RAB9ASMN1; SMN2TP53MAPK1 | |
| SCHEMBL484937 | 0.77 | ALDH1A1 (0.53) | ABL1ABCB1BCRCA12CA1 | |
| SCHEMBL697263 | 0.77 | ABL1 (0.57) | NPC1RAB9ASMN1; SMN2TP53MAPK1 | |
| SCHEMBL197522 | 0.76 | CA1 (0.79) | NPC1RAB9ASMN1; SMN2TP53MAPK1 | |
| SCHEMBL6733562 | 0.76 | CA1 (0.79) | NPC1RAB9ASMN1; SMN2TP53MAPK1 | |
| SCHEMBL9151672 | 0.76 | CA1 (0.79) | NPC1RAB9ASMN1; SMN2TP53MAPK1 | |
| SCHEMBL7703852 | 0.76 | GSTP1 (0.48) | NPC1RAB9ASMN1; SMN2MAOBERN1 | |
| SCHEMBL15971374 | 0.75 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2TP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892795-A1 | PIPERIDINYLPYRAMIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997038992-A1 | PIPERIDINYLPYRAMIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1997-10-23 | — | — | WO | disclosed |