Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | TTK | P33981 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603979 | 0.71 | PFKFB3 (0.31) | — | |
| SCHEMBL5906191 | 0.69 | ALDH1A1 (0.42) | — | |
| SCHEMBL8599564 | 0.69 | HSP90AA1 (0.39) | — | |
| SCHEMBL23564961 | 0.69 | HTT (0.42) | PRMT5WDR77AURKATTKAURKB | |
| SCHEMBL4672478 | 0.68 | GAA (0.43) | AURKA | |
| SCHEMBL29923173 | 0.68 | ROCK2 (0.31) | — | |
| SCHEMBL3532877 | 0.68 | TDP1 (0.50) | KDM5BHCAR2 | |
| SCHEMBL8307507 | 0.68 | PRMT5 (0.33) | PRMT5WDR77 | |
| SCHEMBL8303900 | 0.68 | MAPT (0.36) | PRMT5WDR77 | |
| SCHEMBL8308632 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113301901-B | Tetrazolinone substituted steroids and uses thereof | 北京轩义医药科技有限公司 | 2022-09-09 | — | — | CN | disclosed |
| EP-0695748-B1 | Tetrazolinone herbicides | BAYER AGROCHEM KK (JP) | 1999-05-06 | — | — | EP | disclosed |
| US-5589439-A | HERBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 1996-12-31 | — | — | US | disclosed |
| EP-0695748-A1 | Tetrazolinone herbicides | NIHON BAYER AGROCHEM K.K. (JP) | 1996-02-07 | — | — | EP | disclosed |