Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | USP2 | O75604 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8306889 | 0.82 | RXFP1 (0.58) | MAPK1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL8304200 | 0.70 | MAPT (0.59) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL30058951 | 0.70 | ALDH1A1 (0.68) | MAPK1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL28882091 | 0.69 | ALDH1A1 (0.69) | MAPK1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL8303960 | 0.68 | RXFP1 (0.65) | MAPK1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11545877 | 0.67 | MAPT (0.57) | MAPK1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL21772291 | 0.67 | MEN1 (0.80) | MAPK1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL8305679 | 0.66 | RXFP1 (0.71) | KMT2AALDH1A1MAPTNPSR1LMNA | |
| SCHEMBL27083786 | 0.66 | HPGD (0.68) | MAPK1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL20467488 | 0.65 | HPGD (0.82) | ALDH1A1HPGDMAPTKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004078731-A1 | QUINOLINE-CARBOXYLIC ACIDS AND THE DERIVATIVES THEREOF, A FOCUSED LIBRARY | 'CHEMICAL DIVERSITY RESEARCH INSTITUTE', LTD. (RU) | 2004-09-16 | — | — | WO | disclosed |