Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 14/20 | 0.56 |
| ▸ | CYSLTR1 | Q9Y271 | 14/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8176360 | 1.00 | CYSLTR2 (0.56) | CYSLTR2CYSLTR1MEN1KMT2AALDH1A1 | |
| SCHEMBL8190517 | 0.84 | CYSLTR2 (0.80) | CYSLTR2CYSLTR1 | |
| SCHEMBL6965270 | 0.84 | CYSLTR2 (0.80) | CYSLTR2CYSLTR1 | |
| SCHEMBL28609425 | 0.79 | RAB9A (0.55) | MEN1KMT2AALDH1A1MAPTL3MBTL1 | |
| SCHEMBL6959816 | 0.75 | APP (0.63) | CYSLTR2CYSLTR1MEN1KMT2AMAPT | |
| SCHEMBL6959814 | 0.75 | APP (0.63) | CYSLTR2CYSLTR1MEN1KMT2AMAPT | |
| SCHEMBL6175619 | 0.72 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1MEN1KMT2AALDH1A1 | |
| SCHEMBL6175612 | 0.72 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1MEN1KMT2AALDH1A1 | |
| SCHEMBL6177481 | 0.72 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1 | |
| SCHEMBL6176975 | 0.72 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902007-A1 | CHALCONE DERIVATIVES AND DRUGS CONTAINING THE SAME | KOWA CO. LTD. (JP) | 1999-03-17 | — | — | EP | claimed |