Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 9/20 | 0.36 |
| ▸ | ABCC9 | O60706 | 3/20 | 0.35 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.34 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8307286 | 0.78 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DMALT1 | |
| SCHEMBL8311254 | 0.75 | ALDH1A1 (0.40) | MALT1KDM4EMEN1CYP3A4KMT2A | |
| SCHEMBL9523959 | 0.74 | PDE4A (0.37) | PDE4APDE4BPDE4CPDE4DMALT1 | |
| SCHEMBL8195282 | 0.74 | OPRD1 (0.44) | PDE4APDE4BPDE4CPDE4DABCB1 | |
| SCHEMBL10381365 | 0.74 | ABCC9 (0.41) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL9550599 | 0.74 | KDM4E (0.43) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL7267318 | 0.73 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DMALT1 | |
| SCHEMBL9088354 | 0.72 | ABCC9 (0.38) | PDE4APDE4BPDE4CPDE4DMALT1 | |
| SCHEMBL9524863 | 0.72 | CLK4 (0.40) | PDE4APDE4BPDE4CPDE4DMALT1 | |
| SCHEMBL8642468 | 0.72 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DMALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918056-A1 | Herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1999-05-26 | — | — | EP | disclosed |
| EP-0903346-A1 | SYDNONE IMINE DERIVATIVES | Chugai Seiyaku Kabushiki Kaisha (JP) | 1999-03-24 | — | — | EP | disclosed |