Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 2/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9480021 | 0.91 | REN (0.44) | TDP1ALDH1A1SMN1; SMN2APPCRBN | |
| Hydrochloric Acid SCHEMBL9414486 | 0.89 | TDP1 (0.47) | TDP1ALDH1A1SMN1; SMN2APPCRBN | |
| SCHEMBL7833142 | 0.83 | KMT2A (0.55) | ALDH1A1SMN1; SMN2APPIDO1KMT2A | |
| SCHEMBL8932476 | 0.81 | APP (0.44) | ALDH1A1SMN1; SMN2APPCRBNIDO1 | |
| SCHEMBL9414489 | 0.79 | SIGMAR1 (0.46) | ALDH1A1APPSIGMAR1 | |
| SCHEMBL12012244 | 0.78 | SLC6A2 (0.42) | ALDH1A1SMN1; SMN2APPCRBNIDO1 | |
| SCHEMBL8308762 | 0.78 | IDO1 (0.44) | APPIDO1SIGMAR1KMT2A | |
| SCHEMBL3127110 | 0.78 | GBA1 (0.53) | CRBNSIGMAR1KMT2A | |
| Hydrochloric Acid SCHEMBL3525802 | 0.77 | IDO1 (0.42) | TDP1ALDH1A1SMN1; SMN2APPCRBN | |
| Hydrochloric Acid SCHEMBL3519057 | 0.77 | IDO1 (0.42) | TDP1ALDH1A1SMN1; SMN2APPCRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011148922-A1 | NOVEL QUINAZOLINE COMPOUND | 田辺三菱製薬株式会社 (JP) | 2011-12-01 | — | — | WO | disclosed |
| EP-0903346-A1 | SYDNONE IMINE DERIVATIVES | Chugai Seiyaku Kabushiki Kaisha (JP) | 1999-03-24 | — | — | EP | disclosed |