Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7748818 | 0.90 | KMT2A (0.44) | KMT2AALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL7748820 | 0.90 | KMT2A (0.44) | KMT2AALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL7744266 | 0.78 | KMT2A (0.43) | KMT2AALDH1A1KDM4ETDP1ATM | |
| SCHEMBL7393110 | 0.75 | KMT2A (0.50) | KMT2AALDH1A1TDP1ATMMEN1 | |
| SCHEMBL7748913 | 0.72 | ALDH1A1 (0.45) | KMT2AALDH1A1KDM4ETDP1ATM | |
| SCHEMBL7748918 | 0.72 | ALDH1A1 (0.45) | KMT2AALDH1A1KDM4ETDP1ATM | |
| SCHEMBL4679636 | 0.71 | ATM (0.55) | KMT2AALDH1A1KDM4ETDP1ATM | |
| SCHEMBL1731885 | 0.70 | ALDH1A1 (0.50) | KMT2AALDH1A1KDM4ETDP1ATM | |
| Hydrochloric Acid SCHEMBL8439823 | 0.70 | ATM (0.54) | KMT2AALDH1A1KDM4ETDP1ATM | |
| SCHEMBL7748873 | 0.69 | KMT2A (0.45) | KMT2AALDH1A1KDM4ETDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0952842-A2 | A METHOD OF TREATING CANCER | Merck & Co., Inc. (US) | 1999-11-03 | — | — | EP | claimed |
| WO-1997038664-A2 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 1997-10-23 | — | — | WO | claimed |