Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1298778 | 0.77 | LMNA (0.38) | L3MBTL1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL8770339 | 0.72 | L3MBTL1 (0.40) | L3MBTL1NPC1RAB9AALDH1A1TSHR | |
| SCHEMBL4773510 | 0.71 | KDM4E (0.39) | L3MBTL1NPC1RAB9AALDH1A1TSHR | |
| SCHEMBL28860067 | 0.68 | — | — | |
| SCHEMBL10973432 | 0.65 | NOTUM (0.55) | L3MBTL1RAB9AALDH1A1TSHRHSD17B10 | |
| SCHEMBL30371592 | 0.65 | NOTUM (0.55) | L3MBTL1RAB9AALDH1A1TSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL8995874 | 0.65 | KMT2A (0.43) | L3MBTL1NPC1RAB9AALDH1A1TSHR | |
| SCHEMBL30479438 | 0.62 | CRBN (0.47) | L3MBTL1NPC1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL5610745 | 0.61 | — | — | |
| SCHEMBL27551614 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582182-B1 | 1-Aminoacetamidopyrroles and 1-amino-2-(substituted) pyrroles and their use for the treatment of neurodegenerative dysfunctions | HOECHST MARION ROUSSEL INC (US) | 1999-10-20 | — | — | EP | disclosed |