SCHEMBL8770339

SCHEMBL8770339

CC(=O)Nn1ccccc1=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
HSD17B10 Q99714 5/20 0.39
ALDH1A1 P00352 4/20 0.39
HPGD P15428 3/20 0.39
KDM4E B2RXH2 3/20 0.39
LMNA P02545 1/20 0.39
NAPRT Q6XQN6 1/20 0.38
MAP4K4 O95819 1/20 0.37
ABL1 P00519 1/20 0.37
MAPK8 P45983 1/20 0.37
CSNK1A1 P48729 1/20 0.37
CDK7 P50613 1/20 0.37
TYRO3 Q06418 1/20 0.37
LRRK2 Q5S007 1/20 0.37
AURKB Q96GD4 1/20 0.37
CLK4 Q9HAZ1 1/20 0.37
PIM2 Q9P1W9 1/20 0.37
DYRK1B Q9Y463 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10610999 0.79 L3MBTL1 (0.38) L3MBTL1HSD17B10ALDH1A1KDM4ELMNA
SCHEMBL16654263 0.74
SCHEMBL8307748 0.72 L3MBTL1 (0.36) L3MBTL1NPC1RAB9AHSD17B10ALDH1A1
SCHEMBL22836716 0.71 PSMB1 (0.38) HSD17B10ALDH1A1HPGDKDM4ELMNA
SCHEMBL4773510 0.71 KDM4E (0.39) L3MBTL1NPC1RAB9AHSD17B10ALDH1A1
SCHEMBL8709695 0.69 NPC1 (0.34) L3MBTL1NPC1RAB9AALDH1A1LMNA
SCHEMBL30371592 0.69 NOTUM (0.55) L3MBTL1RAB9AHSD17B10ALDH1A1HPGD
SCHEMBL10973432 0.69 NOTUM (0.55) L3MBTL1RAB9AHSD17B10ALDH1A1HPGD
SCHEMBL8677952 0.68 NOTUM (0.48) HSD17B10ALDH1A1HPGDKDM4ETSHR
SCHEMBL14859990 0.68 CASP3 (0.44) L3MBTL1NPC1RAB9AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0628547-B1 Process for the preparation of N-aminopyridones BASF AG (DE) 1997-09-24 EP disclosed