Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465631 | 0.87 | SMN1; SMN2 (0.41) | HPGDALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL7453967 | 0.71 | RXRA (0.49) | HPGDALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL5212654 | 0.71 | L3MBTL1 (0.40) | ALDH1A1NPC1RAB9AMAPTKDM4E | |
| SCHEMBL7452841 | 0.67 | LMNA (0.47) | HPGDALDH1A1RAB9AKDM4ELMNA | |
| SCHEMBL1362235 | 0.65 | L3MBTL1 (0.43) | ALDH1A1NPC1RAB9AMAPTLMNA | |
| SCHEMBL8304257 | 0.63 | RXRA (0.45) | ALDH1A1NPC1RAB9AHTTLMNA | |
| SCHEMBL10832274 | 0.62 | RXRA (0.57) | RXRARXRBNR4A2KMT2ACYP2C19 | |
| SCHEMBL7463020 | 0.61 | RXFP1 (0.39) | ALDH1A1MAPTTSHRLMNASMN1; SMN2 | |
| SCHEMBL7458187 | 0.60 | L3MBTL1 (0.40) | ALDH1A1NPC1RAB9AMAPTTSHR | |
| SCHEMBL5212017 | 0.59 | RXRA (0.49) | HPGDALDH1A1MAPTTSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891340-A1 | OXAZOLE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997036882-A1 | OXAZOLE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-09 | — | — | WO | disclosed |