SCHEMBL830795

SCHEMBL830795

CN1CN([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c2ncnc(N)c21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.50
DOT1L Q8TEK3 3/20 0.50
STAT6 P42226 2/20 0.50
HIF1A Q16665 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
ALDH1A1 P00352 2/20 0.50
HTT P42858 2/20 0.50
CYP1A2 P05177 1/20 0.50
KDM4E B2RXH2 1/20 0.50
TP53 P04637 1/20 0.50
ALOX15 P16050 1/20 0.50
HSD17B10 Q99714 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
DPP4 P27487 1/20 0.50
MEN1 O00255 1/20 0.50
SLC28A1 O00337 1/20 0.50
MAP3K7 O43318 1/20 0.50
SLC28A2 O43868 1/20 0.50
GAPDH P04406 1/20 0.50
ADORA3 P0DMS8 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL830796 1.00 MAPK1 (0.50) MAPK1DOT1LSTAT6HIF1ATDP1
SCHEMBL453482 0.87 MAPK1 (0.46) MAPK1DOT1LSTAT6HIF1ATDP1
SCHEMBL453483 0.87 MAPK1 (0.46) MAPK1DOT1LSTAT6HIF1ATDP1
SCHEMBL15973691 0.86 ADK (0.50) MAPK1DOT1LSTAT6HIF1ATDP1
SCHEMBL1666083 0.86 HSPA5 (0.52) MAPK1DOT1LSTAT6HIF1ATDP1
SCHEMBL3841527 0.86 DOT1L (0.50) MAPK1DOT1LSTAT6HIF1ATDP1
SCHEMBL1936249 0.86 ADK (0.50) MAPK1DOT1LSTAT6HIF1ATDP1
SCHEMBL1936244 0.86 ADK (0.50) MAPK1DOT1LSTAT6HIF1ATDP1
SCHEMBL724943 0.86 MAPK1 (0.50) MAPK1DOT1LSTAT6HIF1ATDP1
SCHEMBL27767961 0.86 DOT1L (0.50) MAPK1DOT1LSTAT6HIF1ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 318 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250223593-A1 CHEMICALLY MODIFIED SINGLE-STRANDED RNA-EDITING OLIGONUCLEOTIDES PROQR THERAPEUTICS II B.V. (NL) 2025-07-10 US claimed
CN-118613500-A Modified mRNA treatment 沙塔克实验室有限公司 2024-09-06 CN claimed
EP-4379052-A2 MRNA PURIFICATION BY TANGENTIAL FLOW FILTRATION Ethris GmbH (DE) 2024-06-05 EP claimed
EP-4306643-A2 PLASMID CONTAINING A SEQUENCE ENCODING AN MRNA WITH A SEGMENTED POLY(A) TAIL ethris GmbH (DE) 2024-01-17 EP claimed
US-11851656-B2 Chemically modified single-stranded RNA-editing oligonucleotides PROQR THERAPEUTICS II B.V. (NL) 2023-12-26 US claimed
CN-110352244-B Chemically modified RNA editing single stranded oligonucleotides ProQR治疗上市公司Ⅱ 2023-03-21 CN claimed
WO-2022000884-A1 MANNOSE-BASED MRNA TARGETED DELIVERY SYSTEM AND USE THEREOF 深圳市瑞吉生物科技有限公司 2022-01-06 WO claimed
US-20210238597-A1 CHEMICALLY MODIFIED SINGLE-STRANDED RNA-EDITING OLIGONUCLEOTIDES PROQR THERAPEUTICS II B.V. (NL) 2021-08-05 US claimed
US-10941402-B2 Chemically modified single-stranded RNA-editing oligonucleotides PROQR THERAPEUTICS II B.V. (NL) 2021-03-09 US claimed
CN-112390871-A In vivo production of proteins 现代泰克斯公司 2021-02-23 CN claimed
EP-3507366-B1 CHEMICALLY MODIFIED SINGLE-STRANDED RNA-EDITING OLIGONUCLEOTIDES PROQR THERAPEUTICS II BV (NL) 2020-10-07 EP claimed
CN-110352244-A The single-stranded oligonucleotide of the editor RNA of chemical modification ProQR治疗上市公司Ⅱ 2019-10-18 CN claimed
US-20190218552-A1 CHEMICALLY MODIFIED SINGLE-STRANDED RNA-EDITING OLIGONUCLEOTIDES PROQR THERAPEUTICS II B.V. (NL) 2019-07-18 US claimed
EP-3507366-A1 CHEMICALLY MODIFIED SINGLE-STRANDED RNA-EDITING OLIGONUCLEOTIDES ProQR Therapeutics II B.V. (NL) 2019-07-10 EP claimed
WO-2018041973-A1 CHEMICALLY MODIFIED SINGLE-STRANDED RNA-EDITING OLIGONUCLEOTIDES PROQR THERAPEUTICS II B.V. (NL) 2018-03-08 WO claimed
EP-4746905-A1 RSV VACCINE Astrazeneca AB (SE) 2026-05-27 EP disclosed
CN-113396219-B Purification of mRNA by tangential flow filtration ETHRIS GMBH (DE) 2026-05-26 CN disclosed
EP-0691980-B1 7-DEAZAPURINE MODIFIED OLIGONUCLEOTIDES SANOFI SA (FR) 1997-06-04 EP disclosed
EP-0691980-A1 7-DEAZAPURINE MODIFIED OLIGONUCLEOTIDES STERLING WINTHROP INC (US) 1996-01-17 EP disclosed
WO-1994022892-A1 7-DEAZAPURINE MODIFIED OLIGONUCLEOTIDES STERLING WINTHROP INC. (US) 1994-10-13 WO disclosed