Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 5/20 | 0.50 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | STAT6 | P42226 | 2/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.50 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.50 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | ROS1 | P08922 | 1/20 | 0.50 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.50 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.50 |
| ▸ | CLK2 | P49760 | 1/20 | 0.50 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1936244 | 1.00 | ADK (0.50) | ADKDOT1LMAPK1HIF1ASTAT6 | |
| SCHEMBL15973691 | 0.86 | ADK (0.50) | ADKDOT1LMAPK1HIF1ASTAT6 | |
| SCHEMBL27767961 | 0.86 | DOT1L (0.50) | ADKDOT1LMAPK1HIF1ASTAT6 | |
| SCHEMBL3841527 | 0.86 | DOT1L (0.50) | ADKDOT1LMAPK1HIF1ASTAT6 | |
| SCHEMBL830796 | 0.86 | MAPK1 (0.50) | ADKDOT1LMAPK1HIF1ASTAT6 | |
| SCHEMBL724943 | 0.86 | MAPK1 (0.50) | ADKDOT1LMAPK1HIF1ASTAT6 | |
| SCHEMBL1666083 | 0.86 | HSPA5 (0.52) | ADKDOT1LMAPK1HIF1ASTAT6 | |
| SCHEMBL830795 | 0.86 | MAPK1 (0.50) | ADKDOT1LMAPK1HIF1ASTAT6 | |
| Ammonia Solution, Strong SCHEMBL28844518 | 0.85 | HSPA5 (0.51) | ADKDOT1LMAPK1HIF1ASTAT6 | |
| SCHEMBL1665379 | 0.85 | HSPA5 (0.51) | ADKDOT1LMAPK1HIF1ASTAT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220411458-A1 | TRANSLOCATION CONTROL ELEMENTS, REPORTER CODES, AND FURTHER MEANS FOR TRANSLOCATION CONTROL FOR USE IN NANOPORE SEQUENCING | Roche Sequencing Solutions, Inc. | 2022-12-29 | — | — | US | disclosed |
| EP-3972976-A1 | TRANSLOCATION CONTROL ELEMENTS, REPORTER CODES, AND FURTHER MEANS FOR TRANSLOCATION CONTROL FOR USE IN NANOPORE SEQUENCING | Stratos Genomics Inc. (US) | 2022-03-30 | — | — | EP | disclosed |
| CN-114096540-A | Translocation control elements, reporter codes, and other means for translocation control for nanopore sequencing | 斯特拉托斯基因公司 | 2022-02-25 | — | — | CN | disclosed |
| WO-2020236526-A1 | TRANSLOCATION CONTROL ELEMENTS, REPORTER CODES, AND FURTHER MEANS FOR TRANSLOCATION CONTROL FOR USE IN NANOPORE SEQUENCING | STRATOS GENOMICS, INC. (US) | 2020-11-26 | — | — | WO | disclosed |
| EP-2707483-B1 | METHODS AND MATERIALS FOR NUCLEIC ACID MANIPULATION | RWTH AACHEN UNIV (DE) | 2017-10-18 | — | — | EP | disclosed |
| EP-1540013-B1 | EVOLVING NEW MOLECULAR FUNCTION | HARVARD COLLEGE (US) | 2015-07-08 | — | — | EP | disclosed |
| WO-2014128289-A1 | BIOMEDICAL DEVICE IMPLANTABLE IN BONE AND/OR CARTILAGINOUS TISSUE, AND CORRESPONDING METHOD TO MANUFACTURE SAID BIOMEDICAL DEVICE | LUMETTI, SIMONE (IT) | 2014-08-28 | — | — | WO | disclosed |
| EP-1423400-B2 | EVOLVING NEW MOLECULAR FUNCTION | HARVARD COLLEGE (US) | 2013-05-22 | — | — | EP | disclosed |
| US-20120295311-A1 | Methods and Materials for Nucleic Acid Manipulation | BASF SE (DE) | 2012-11-22 | — | — | US | disclosed |
| US-20120165228-A1 | EVOLVING NEW MOLECULAR FUNCTION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2012-06-28 | — | — | US | disclosed |
| US-20050042669-A1 | Evolving new molecular function | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2005-02-24 | — | — | US | disclosed |
| US-20050025766-A1 | Evolving new molecular function | LIU DAVID R (US) | 2005-02-03 | — | — | US | disclosed |
| EP-1423400-A4 | EVOLVING NEW MOLECULAR FUNCTION | HARVARD COLLEGE (US) | 2004-12-01 | — | — | EP | disclosed |
| US-20040180412-A1 | Evolving new molecular function | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2004-09-16 | — | — | US | disclosed |
| EP-1423400-A2 | EVOLVING NEW MOLECULAR FUNCTION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2004-06-02 | — | — | EP | disclosed |
| WO-2004016767-A2 | EVOLVING NEW MOLECULAR FUNCTION | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2004-02-26 | — | — | WO | disclosed |
| US-20030113738-A1 | Evolving new molecular function | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2003-06-19 | — | — | US | disclosed |
| US-20030013089-A1 | Dye-labeled ribonucleotide triphosphates | APPLIED BIOSYSTEMS, LLC | 2003-01-16 | — | — | US | disclosed |
| WO-2003000841-A2 | DYE-LABELED RIBONUCLEOTIDE TRIPHOSPHATES | APPLERA CORPORATION (US) | 2003-01-03 | — | — | WO | disclosed |
| WO-2002074929-A2 | EVOLVING NEW MOLECULAR FUNCTION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2002-09-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220411458-A1 | TRANSLOCATION CONTROL ELEMENTS, REPORTER CODES, AND FURTHER MEANS FOR TRANSLOCATION CONTROL FOR USE IN NANOPORE SEQUENCING | PHAX, DNTT, NSUN3 | ADK 1704/4885DOT1L 4195/4885MAPK1 1934/4885 |
| US-20030013089-A1 | Dye-labeled ribonucleotide triphosphates | DUT, POLRMT, SAMHD1 | ADK 327/4885DOT1L 1277/4885MAPK1 4705/4885 |
| US-20050025766-A1 | Evolving new molecular function | POLI, PCNA, POLK | ADK 769/4885DOT1L 4185/4885MAPK1 3736/4885 |
| US-20120165228-A1 | EVOLVING NEW MOLECULAR FUNCTION | POLI, PCNA, POLK | ADK 769/4885DOT1L 4185/4885MAPK1 3736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.