Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 7/20 | 0.54 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.54 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.54 |
| ▸ | GABRA2 | P47869 | 7/20 | 0.54 |
| ▸ | GABRB2 | P47870 | 7/20 | 0.54 |
| ▸ | GABRP | O00591 | 6/20 | 0.54 |
| ▸ | GABRD | O14764 | 6/20 | 0.54 |
| ▸ | GABRB1 | P18505 | 6/20 | 0.54 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.54 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.54 |
| ▸ | GABRA4 | P48169 | 6/20 | 0.54 |
| ▸ | GABRE | P78334 | 6/20 | 0.54 |
| ▸ | GABRA6 | Q16445 | 6/20 | 0.54 |
| ▸ | GABRG1 | Q8N1C3 | 6/20 | 0.54 |
| ▸ | GABRG3 | Q99928 | 6/20 | 0.54 |
| ▸ | GABRQ | Q9UN88 | 6/20 | 0.54 |
| ▸ | NMUR2 | Q9GZQ4 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8047 | 0.90 | GABRP (0.56) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL8545 | 0.90 | GABRP (0.41) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL8059 | 0.89 | GABRP (0.53) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL8679 | 0.87 | GABRP (0.55) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL9066 | 0.80 | GABRP (0.59) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL9227 | 0.79 | NMUR2 (0.49) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL13726320 | 0.79 | NMUR2 (0.39) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL8307 | 0.76 | GABRP (0.54) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL8661 | 0.76 | NSD2 (0.49) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL8109 | 0.76 | NMUR2 (0.54) | GABRA1GABRA5GABRA3GABRA2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496567-A2 | NOVEL BENZOPYRAN KINASE MODULATORS | Rhizen Pharmaceuticals S.A. (CH) | 2012-09-12 | — | — | EP | disclosed |
| WO-2011055215-A2 | NOVEL KINASE MODULATORS | INCOZEN THERAPEUTICS PVT. LTD. (IN) | 2011-05-12 | — | — | WO | disclosed |