Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMUR2 | Q9GZQ4 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8109 | 0.87 | NMUR2 (0.54) | NMUR2HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8360 | 0.84 | NMUR2 (0.51) | NMUR2HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9012 | 0.83 | MAPK14 (0.51) | MAPTGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9471 | 0.81 | NMUR2 (0.54) | NMUR2HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8732 | 0.81 | NMUR2 (0.54) | NMUR2HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL30694899 | 0.81 | NMUR2 (0.54) | NMUR2HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9595 | 0.81 | CA1 (0.54) | HPGDSMN1; SMN2NPC1RAB9ANTRK1 | |
| SCHEMBL8545 | 0.81 | GABRP (0.41) | NMUR2HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8310 | 0.79 | GABRP (0.48) | HPGDSMN1; SMN2KDM4ECYP3A4HSD17B10 | |
| SCHEMBL8308 | 0.79 | GABRA1 (0.54) | NMUR2HPGDSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496567-A2 | NOVEL BENZOPYRAN KINASE MODULATORS | Rhizen Pharmaceuticals S.A. (CH) | 2012-09-12 | — | — | EP | claimed |
| WO-2011055215-A2 | NOVEL KINASE MODULATORS | INCOZEN THERAPEUTICS PVT. LTD. (IN) | 2011-05-12 | — | — | WO | claimed |