Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 9/20 | 0.47 |
| ▸ | MAOB | P27338 | 8/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 4/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3870625 | 1.00 | MAOA (0.47) | MAOAMAOBLOXL2KDM1ATAAR1 | |
| SCHEMBL4912036 | 1.00 | MAOA (0.47) | MAOAMAOBLOXL2KDM1ATAAR1 | |
| SCHEMBL23611125 | 0.87 | MAOA (0.48) | MAOAMAOBLOXL2KDM1A | |
| SCHEMBL3886896 | 0.86 | MAOA (0.39) | MAOAMAOBLOXL2KDM1ATAAR1 | |
| SCHEMBL9384798 | 0.79 | MAOA (0.42) | MAOAMAOBKDM1ANOS2 | |
| SCHEMBL8990310 | 0.78 | MAOA (0.41) | MAOAMAOBKDM1A | |
| SCHEMBL7269135 | 0.74 | KDM1A (0.43) | MAOAMAOBLOXL2KDM1ATAAR1 | |
| SCHEMBL476346 | 0.73 | TDP1 (0.38) | MAOAMAOBTAAR1SMN1; SMN2 | |
| SCHEMBL7402503 | 0.72 | MAOA (0.48) | MAOAMAOBLOXL2KDM1ATAAR1 | |
| Ammonia Solution, Strong SCHEMBL14691839 | 0.72 | MAOA (0.48) | MAOAMAOBKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901480-A4 | PROCESS FOR PREPARING OXIRANEMETHANAMINE DERIVATIVES | BOEHRINGER INGELHEIM PHARMA (US) | 1999-11-24 | — | — | EP | disclosed |
| EP-0901480-A1 | PROCESS FOR PREPARING OXIRANEMETHANAMINE DERIVATIVES | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997042180-A1 | PROCESS FOR PREPARING OXIRANEMETHANAMINE DERIVATIVES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1997-11-13 | — | — | WO | disclosed |