Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.41 |
| ▸ | MAOB | P27338 | 7/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 4/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23611125 | 0.85 | MAOA (0.48) | MAOAMAOBTSHRKDM1ALMNA | |
| SCHEMBL476346 | 0.83 | TDP1 (0.38) | MAOAMAOBLMNAL3MBTL1MEN1 | |
| SCHEMBL10371092 | 0.80 | TSHR (0.54) | TSHRTACR1LMNA | |
| SCHEMBL4912036 | 0.78 | MAOA (0.47) | MAOAMAOBKDM1A | |
| SCHEMBL3870625 | 0.78 | MAOA (0.47) | MAOAMAOBKDM1A | |
| SCHEMBL9384798 | 0.78 | MAOA (0.42) | MAOAMAOBTSHRKDM1ALMNA | |
| SCHEMBL8308191 | 0.78 | MAOA (0.47) | MAOAMAOBKDM1A | |
| SCHEMBL476360 | 0.77 | HPGD (0.49) | MAOAMAOBTSHRLMNAL3MBTL1 | |
| SCHEMBL8558732 | 0.74 | TSHR (0.47) | TSHRTACR1LMNANPSR1MEN1 | |
| SCHEMBL7404874 | 0.73 | TSHR (0.45) | MAOAMAOBTSHRKDM1ATACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532225-A | TREATMENT OF HERPES VIRUS | SRI INTERNATIONAL (US) | 1996-07-02 | — | — | US | disclosed |
| WO-1994003466-A1 | ACYCLIC PURINE PHOSPHONATE NUCLEOTIDE ANALOGS AS ANTIVIRAL AGENTS, AND RELATED SYNTHETIC METHODS | SRI INTERNATIONAL (US) | 1994-02-17 | — | — | WO | disclosed |