Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8308218 | 1.00 | ALOX5 (0.51) | ALOX5EPHX2HDAC3NCOR1HDAC2 | |
| SCHEMBL8309230 | 0.80 | ALOX5 (0.51) | ALOX5EPHX2 | |
| SCHEMBL8309228 | 0.80 | ALOX5 (0.51) | ALOX5EPHX2 | |
| SCHEMBL8610041 | 0.80 | ALOX5 (0.51) | ALOX5EPHX2 | |
| SCHEMBL8941430 | 0.74 | ALOX5 (0.51) | ALOX5EPHX2 | |
| SCHEMBL4729578 | 0.72 | ALOX5 (0.44) | ALOX5EPHX2 | |
| SCHEMBL5086216 | 0.72 | ALOX5 (0.44) | ALOX5EPHX2 | |
| SCHEMBL9048629 | 0.71 | ALOX5 (0.69) | ALOX5EPHX2 | |
| SCHEMBL8659861 | 0.71 | MAPT (0.51) | ALOX5EPHX2HDAC3HDAC2HDAC8 | |
| SCHEMBL8650521 | 0.71 | MAPT (0.51) | ALOX5EPHX2HDAC3HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832078-B1 | N-HYDROXYUREAS AS ANTIINFLAMMATORY AGENTS | PFIZER (US) | 1999-10-20 | — | — | EP | disclosed |