Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 10/20 | 0.46 |
| ▸ | PPARA | Q07869 | 8/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941348 | 0.92 | PPARG (0.48) | ALOX5PPARGPPARAEPHX2 | |
| SCHEMBL8941364 | 0.88 | PPARG (0.47) | ALOX5PPARGPPARAPTPN1FAAH | |
| SCHEMBL8941747 | 0.81 | ALOX5 (0.53) | ALOX5PPARGPPARAEPHX2 | |
| SCHEMBL8941351 | 0.80 | PPARG (0.48) | PPARGPPARA | |
| SCHEMBL8610041 | 0.78 | ALOX5 (0.51) | ALOX5EPHX2 | |
| SCHEMBL8309228 | 0.78 | ALOX5 (0.51) | ALOX5EPHX2 | |
| SCHEMBL8309230 | 0.78 | ALOX5 (0.51) | ALOX5EPHX2 | |
| SCHEMBL8308216 | 0.74 | ALOX5 (0.51) | ALOX5EPHX2 | |
| SCHEMBL8308218 | 0.74 | ALOX5 (0.51) | ALOX5EPHX2 | |
| SCHEMBL8659861 | 0.73 | MAPT (0.51) | ALOX5EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552424-A | Isoxazolines as antiinflammatory agents | PFIZER INC. (US) | 1996-09-03 | — | — | US | disclosed |