Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11879869 | 0.89 | HTR2A (0.56) | KDM4EHTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL8308417 | 0.84 | KDM4E (0.67) | KDM4EMEN1ALDH1A1KMT2ATDP1 | |
| SCHEMBL9397288 | 0.83 | SIGMAR1 (0.63) | SIGMAR1EBPTMEM97 | |
| SCHEMBL7297538 | 0.81 | SLC6A4 (0.49) | KDM4EHTR2AHTR2CHTR2BMEN1 | |
| Hydrochloric Acid SCHEMBL9780460 | 0.80 | APOBEC3A (0.50) | KDM4EHTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL9397184 | 0.79 | SIGMAR1 (0.57) | SIGMAR1EBPTMEM97 | |
| SCHEMBL1298962 | 0.76 | SIGMAR1 (0.76) | SIGMAR1EBPTMEM97 | |
| SCHEMBL25634998 | 0.75 | HRH3 (0.51) | KDM4EHTR2ASMN1; SMN2SIGMAR1EBP | |
| SCHEMBL14375340 | 0.75 | KDM4E (0.60) | KDM4EHTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL27690553 | 0.75 | POLB (0.53) | KDM4EHTR2ASMN1; SMN2TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903346-A1 | SYDNONE IMINE DERIVATIVES | Chugai Seiyaku Kabushiki Kaisha (JP) | 1999-03-24 | — | — | EP | disclosed |