Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.62 |
| ▸ | KIF11 | P52732 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | FPR2 | P25090 | 5/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12377252 | 0.84 | EPHX2 (0.70) | EPHX2KIF11MEN1KMT2AMAPT | |
| SCHEMBL19549502 | 0.82 | FPR2 (0.66) | EPHX2MEN1KMT2ACA12CA1 | |
| SCHEMBL29687050 | 0.81 | EPHX2 (0.65) | EPHX2MAPTFPR2RAB9A | |
| SCHEMBL29687180 | 0.81 | KIF11 (0.51) | KIF11KDM4EMAPTCA12CA1 | |
| SCHEMBL29687222 | 0.81 | KIF11 (0.51) | KIF11KDM4EMAPTCA12CA1 | |
| SCHEMBL29687159 | 0.80 | MDM2 (0.58) | KDM4ESMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL29687046 | 0.80 | KIF11 (0.58) | EPHX2KIF11SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6873113 | 0.79 | HSD17B10 (0.62) | EPHX2KDM4ESMN1; SMN2KMT2AMAPT | |
| SCHEMBL1903330 | 0.79 | HSD17B10 (0.62) | EPHX2KDM4ESMN1; SMN2KMT2AMAPT | |
| SCHEMBL28729179 | 0.78 | EPHX2 (1.00) | EPHX2KIF11MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920424-A1 | NON-PEPTIDE BOMBESIN RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1999-06-09 | — | — | EP | claimed |
| WO-1998007718-A1 | NON-PEPTIDE BOMBESIN RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1998-02-26 | — | — | WO | claimed |
| EP-3265083-B1 | SUBSTITUTED UREA DEPSIPEPTIDE ANALOGS AS ACTIVATORS OF THE CLPP ENDOPEPTIDASE | ST JUDE CHILDRENS RES HOSPITAL (US) | 2022-07-06 | — | — | EP | disclosed |
| EP-0920424-A1 | NON-PEPTIDE BOMBESIN RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998007718-A1 | NON-PEPTIDE BOMBESIN RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1998-02-26 | — | — | WO | disclosed |