Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.32 |
| ▸ | AURKA | O14965 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8308579 | 0.88 | EGFR (0.39) | CCR9FYNLMNAMAPTATM | |
| SCHEMBL8304442 | 0.81 | EGFR (0.41) | CCR9LMNARPS6KB1AURKA | |
| SCHEMBL8304201 | 0.74 | CCR9 (0.35) | CCR9FYNMAPTRETRPS6KB1 | |
| SCHEMBL9528635 | 0.72 | EGFR (0.40) | RPS6KB1AURKA | |
| SCHEMBL9085869 | 0.69 | GALR3 (0.45) | LMNAL3MBTL1AURKATP53 | |
| SCHEMBL9526898 | 0.68 | RPS6KB1 (0.39) | AKT1MAPTRPS6KB1AURKA | |
| SCHEMBL15684929 | 0.68 | CNR1 (0.48) | — | |
| SCHEMBL9215503 | 0.68 | EGFR (0.47) | AKT1LMNAMAPTRPS6KB1 | |
| SCHEMBL9869764 | 0.68 | CRHR1 (0.36) | — | |
| SCHEMBL7992661 | 0.67 | KDM4E (0.41) | FYNMAPTRPS6KB1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555388-B1 | INSECTICIDAL, ACARICIDAL AND FUNGICIDAL AMINOPYRIMIDINES | DU PONT (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1992008704-A1 | INSECTICIDAL, ACARICIDAL AND FUNGICIDAL AMINOPYRIMIDINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-05-29 | — | — | WO | disclosed |