Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 16/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 2/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8304442 | 0.91 | EGFR (0.41) | EGFRP2RX3CRHR1AURKARPS6KB1 | |
| SCHEMBL9403796 | 0.83 | EGFR (0.55) | EGFRCRHR1AURKARPS6KB1 | |
| SCHEMBL9215503 | 0.76 | EGFR (0.47) | EGFRCRHR1RPS6KB1 | |
| SCHEMBL9523092 | 0.75 | EGFR (0.46) | EGFRCRHR1RPS6KB1 | |
| SCHEMBL7992661 | 0.73 | KDM4E (0.41) | EGFRCRHR1RPS6KB1 | |
| SCHEMBL8304201 | 0.73 | CCR9 (0.35) | AURKARPS6KB1 | |
| SCHEMBL8303141 | 0.72 | EGFR (0.38) | EGFRP2RX3CRHR1RPS6KB1 | |
| SCHEMBL28943346 | 0.72 | AURKA (0.40) | EGFRCRHR1AURKARPS6KB1 | |
| SCHEMBL28943348 | 0.72 | AURKA (0.40) | EGFRCRHR1AURKARPS6KB1 | |
| SCHEMBL8308475 | 0.72 | CCR9 (0.37) | AURKARPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555388-A1 | INSECTICIDAL, ACARICIDAL AND FUNGICIDAL AMINOPYRIMIDINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-08-18 | — | — | EP | disclosed |