Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 6/20 | 0.53 |
| ▸ | METAP2 | P50579 | 3/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | NLN | Q9BYT8 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8307193 | 0.94 | TACR1 (0.49) | TACR1METAP2MMP9NLNRAB9A | |
| SCHEMBL7363741 | 0.91 | TACR1 (0.52) | TACR1METAP2MMP9NLNRAB9A | |
| SCHEMBL7354811 | 0.88 | TACR1 (0.50) | TACR1METAP2MMP9NLNRAB9A | |
| SCHEMBL7361608 | 0.85 | RAB9A (0.55) | TACR1RAB9A | |
| SCHEMBL7361754 | 0.84 | TACR1 (0.47) | TACR1METAP2MMP9NLN | |
| SCHEMBL7359125 | 0.82 | TACR1 (0.45) | TACR1METAP2MMP9NLN | |
| SCHEMBL8305264 | 0.81 | PSMB5 (0.47) | — | |
| SCHEMBL7363278 | 0.79 | TACR1 (0.47) | TACR1MMP9RAB9A | |
| SCHEMBL7353122 | 0.77 | RAB9A (0.53) | TACR1RAB9A | |
| SCHEMBL8309499 | 0.75 | MEN1 (0.58) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753003-B1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-06-16 | — | — | EP | disclosed |
| US-5668128-A | INHIBITORS OF THIOL PROTEASE, PROPHYLAXIS AND TREATMENT OF BONE DISEASES, OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-09-16 | — | — | US | disclosed |