Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | TACR1 | P25103 | 8/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363278 | 0.89 | TACR1 (0.47) | RAB9ATACR1 | |
| SCHEMBL7353122 | 0.89 | RAB9A (0.53) | RAB9ATACR1HPGD | |
| SCHEMBL7364215 | 0.86 | RAB9A (0.51) | RAB9ATACR1HPGD | |
| SCHEMBL8308617 | 0.85 | TACR1 (0.53) | RAB9ATACR1 | |
| SCHEMBL7360191 | 0.84 | OPRM1 (0.51) | RAB9ATACR1 | |
| SCHEMBL7355167 | 0.82 | KMT2A (0.46) | RAB9ATACR1 | |
| SCHEMBL8307193 | 0.80 | TACR1 (0.49) | RAB9ATACR1 | |
| SCHEMBL7361179 | 0.78 | MME (0.53) | — | |
| SCHEMBL7363283 | 0.78 | TACR1 (0.46) | RAB9ATACR1 | |
| SCHEMBL7355198 | 0.77 | MEN1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753003-B1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-06-16 | — | — | EP | disclosed |
| US-5668128-A | INHIBITORS OF THIOL PROTEASE, PROPHYLAXIS AND TREATMENT OF BONE DISEASES, OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-09-16 | — | — | US | disclosed |
| EP-0753003-A1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995028416-A1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-26 | — | — | WO | disclosed |