Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8308867 | 1.00 | SIGMAR1 (0.44) | SIGMAR1HPGDCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL8308864 | 1.00 | SIGMAR1 (0.44) | SIGMAR1HPGDCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL18587701 | 0.75 | CHRNB2 (0.52) | CHRNB2CHRNA7CHRNA4ALDH1A1 | |
| SCHEMBL18588003 | 0.75 | CHRNB2 (0.52) | CHRNB2CHRNA7CHRNA4ALDH1A1 | |
| SCHEMBL19615663 | 0.75 | CHRNB2 (0.52) | CHRNB2CHRNA7CHRNA4ALDH1A1 | |
| SCHEMBL18588004 | 0.75 | CHRNB2 (0.52) | CHRNB2CHRNA7CHRNA4ALDH1A1 | |
| SCHEMBL12256049 | 0.73 | TSHR (0.55) | SIGMAR1HPGDCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL11447207 | 0.73 | SPHK2 (0.64) | — | |
| SCHEMBL4931440 | 0.73 | SPHK2 (0.64) | — | |
| SCHEMBL699162 | 0.72 | CHRNB2 (0.56) | SIGMAR1HPGDCHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607374-B1 | NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS | PO HANG IRON & STEEL (KR) | 1999-04-07 | — | — | EP | disclosed |
| US-5700817-A | Cyclic lipid derivatives as potent PAF antagonists | POHANG IRON & STEEL CO., LTD. (KR) | 1997-12-23 | — | — | US | disclosed |
| US-5610310-A | Cyclic lipid derivatives as potent PAF antagonists | POHANG IRON & STEEL CO., LTD (KR) | 1997-03-11 | — | — | US | disclosed |