SCHEMBL8308905

SCHEMBL8308905

O=C(O)C(Br)CC(Br)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.61
TSHR P16473 3/20 0.61
THRB P10828 1/20 0.50
RECQL P46063 1/20 0.50
CYP2C19 P33261 1/20 0.47
LCK P06239 1/20 0.44
PPARD Q03181 1/20 0.44
ZDHHC20 Q5W0Z9 1/20 0.44
ZDHHC2 Q9UIJ5 1/20 0.44
RNPEP Q9H4A4 1/20 0.33
OR51E2 Q9H255 1/20 0.33
SLC7A5 Q01650 1/20 0.33
LMNA P02545 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ENPEP Q07075 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28638484 1.00 ALDH1A1 (0.61) ALDH1A1TSHRTHRBRECQLCYP2C19
SCHEMBL9352399 0.84 ALDH1A1 (0.46) ALDH1A1TSHRTHRBRECQLCYP2C19
SCHEMBL489803 0.82
SCHEMBL489804 0.82
SCHEMBL9869901 0.82
SCHEMBL8370155 0.82
SCHEMBL2637647 0.82
SCHEMBL27575981 0.80 ZDHHC7 (0.47) ALDH1A1TSHRTHRBRECQLCYP2C19
SCHEMBL310533 0.80
Hydrochloric Acid SCHEMBL18580855 0.80 RNPEP (0.48) ALDH1A1TSHRTHRBRECQLCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0615688-B1 An industrial microbicide and a method for killing microbes for industrial use KATAYAMA CHEMICAL WORKS CO (JP) 1997-11-12 EP claimed
CN-113603683-A Substituted phenyl oxazolidinones for antimicrobial therapy 结核病药物开发全球联盟公司 2021-11-05 CN disclosed
CN-108348507-B Substituted phenyl oxazolidinones for antimicrobial therapy 结核病药物开发全球联盟公司 2021-10-08 CN disclosed
CN-1984981-B Lubricating oil additive containing acrylic polymer and lubricating oil composition KURARAY CO 2010-11-17 CN disclosed
CN-100430426-C Thermoplastic elastomer composition and molded article KANEGAFUCHI CHEMICAL IND (JP) 2008-11-05 CN disclosed
CN-101016400-A Thermoplastic resin composition KANEGAFUCHI CHEMICAL IND (JP) 2007-08-15 CN disclosed
CN-1984981-A Lubricating oil additive containing acrylic polymer and lubricating oil composition KURARAY CO (JP) 2007-06-20 CN disclosed
CN-1315949-C Thermoplastic resin composition KANEGAFUCHI CHEMICAL IND (JP) 2007-05-16 CN disclosed
CN-1509318-A Thermoplastic resin composition ��Ԩ��ѧ��ҵ��ʽ���� 2004-06-30 CN disclosed
EP-0607374-B1 NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS PO HANG IRON & STEEL (KR) 1999-04-07 EP disclosed
EP-0571313-B1 An industrial microbicide and a method for killing microbes for industrial use KATAYAMA CHEMICAL WORKS CO (JP) 1999-03-03 EP disclosed
US-5411990-A Dioxime derivative YOSHITOMI PHARMACEUTICAL INDUSTRIES LTD. (JP) 1995-05-02 US disclosed
EP-0299513-B1 Azetidine derivatives, compositions and their use FIDIA GEORGETOWN INST (US) 1994-10-05 EP disclosed
EP-0607374-A1 NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS POHANG IRON & STEEL CO., LTD. (KR) 1994-07-27 EP disclosed
WO-1994000447-A1 NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS POHANG IRON & STEEL CO., LTD. (KR) 1994-01-06 WO disclosed
EP-0571313-A2 An industrial microbicide and a method for killing microbes for industrial use KATAYAMA CHEMICAL, INC. (JP) 1993-11-24 EP disclosed
US-4990504-A Modulate excitatory amino acid receptor system FIDIA-GEORGETOWN INSTITUTE FOR THE NEUROSCIENCES (US) 1991-02-05 US disclosed
US-4946839-A ALZHEIMER'S DISEASE FIDIA-GEORGETOWN INSTITUTE FOR THE NEUROSCIENCES (US) 1990-08-07 US disclosed
EP-0299513-A1 Azetidine derivatives, compositions and their use FIDIA-GEORGETOWN INSTITUTE FOR THE NEUROSCIENCES (US) 1989-01-18 EP disclosed