⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL489803 | 0.83 | — | — | |
| SCHEMBL2637647 | 0.83 | — | — | |
| SCHEMBL489804 | 0.83 | — | — | |
| SCHEMBL28638484 | 0.82 | ALDH1A1 (0.61) | — | |
| SCHEMBL8308905 | 0.82 | ALDH1A1 (0.61) | — | |
| SCHEMBL27949976 | 0.81 | ALDH1A1 (0.48) | — | |
| Hydrochloric Acid SCHEMBL18580855 | 0.81 | RNPEP (0.48) | — | |
| SCHEMBL310533 | 0.81 | — | — | |
| SCHEMBL4955010 | 0.79 | ALDH1A1 (0.46) | — | |
| SCHEMBL27533786 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110028441-A | A kind of fluoro- 2-(1- bromine cyclopropyl of 5-) pyridine synthetic method | 江苏工程职业技术学院 | 2019-07-19 | — | — | CN | claimed |
| US-4973708-A | TRANSDERMAL ENHANCER FOR PENETRATION OF DRUGS THROUGH THE SKIN | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1990-11-27 | — | — | US | claimed |
| EP-3623372-A1 | PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS | Forma Therapeutics, Inc. (US) | 2020-03-18 | — | — | EP | disclosed |
| CN-110446700-A | Compound | GLAXOSMITHKLINE IP DEV LTD | 2019-11-12 | — | — | CN | disclosed |
| EP-3240791-B1 | PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2019-11-06 | — | — | EP | disclosed |
| CN-110028441-A | A kind of fluoro- 2-(1- bromine cyclopropyl of 5-) pyridine synthetic method | 江苏工程职业技术学院 | 2019-07-19 | — | — | CN | disclosed |
| CN-104524590-B | The purposes of crosslinking agent and they | 伊缪诺金公司 | 2019-06-21 | — | — | CN | disclosed |
| CN-105745214-B | Tricyclic piperidine compounds | 埃科特莱茵药品有限公司 | 2019-02-19 | — | — | CN | disclosed |
| CN-105517574-B | The combination product of hepatitis C virus inhibitors | 百时美施贵宝公司 | 2019-01-18 | — | — | CN | disclosed |
| CN-104524592-B | Crosslinking agent and their purposes | 伊缪诺金公司 | 2018-06-05 | — | — | CN | disclosed |
| CN-108112251-A | NRF2 conditioning agents | 葛兰素史克知识产权发展有限公司 | 2018-06-01 | — | — | CN | disclosed |
| CN-108064223-A | FXR (NR1H4) modulating compound of hydroxyl | 吉利德科学公司 | 2018-05-22 | — | — | CN | disclosed |
| CN-107922353-A | IDO inhibitor | 百时美施贵宝公司 | 2018-04-17 | — | — | CN | disclosed |
| US-5032402-A | 3-hydroxy-N-methylpyrrolidone and use as transdermal enhancer | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1991-07-16 | — | — | US | disclosed |
| US-4973708-A | TRANSDERMAL ENHANCER FOR PENETRATION OF DRUGS THROUGH THE SKIN | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1990-11-27 | — | — | US | disclosed |