SCHEMBL489804

SCHEMBL489804

CC(C)CC(Br)C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2637647 1.00
SCHEMBL489803 1.00
Hydrochloric Acid SCHEMBL18580855 0.97 RNPEP (0.48)
SCHEMBL9869901 0.83
SCHEMBL28638484 0.82 ALDH1A1 (0.61)
SCHEMBL8308905 0.82 ALDH1A1 (0.61)
SCHEMBL27949976 0.81 ALDH1A1 (0.48)
SCHEMBL310533 0.81
SCHEMBL4955010 0.79 ALDH1A1 (0.46)
SCHEMBL27533786 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 361 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011141923-A2 IMPROVED SYNTHESIS OF OPTICALLY PURE (S) - 3-CYANO-5-METHYL-HEXANOIC ACID ALKYL ESTER, AN INTERMEDIATE OF (S)- PREGABALIN LUPIN LIMITED (IN) 2011-11-17 WO claimed
EP-3773573-B1 ANTAGONISTS OF HUMAN INTEGRIN (ALPHA4)(BETA7) MORPHIC THERAPEUTIC INC (US) 2026-03-18 EP disclosed
EP-4204397-B1 INHIBITORS OF PSEUDOMONAS AERUGINOSA VIRULENCE FACTOR LASB HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) 2025-12-03 EP disclosed
US-20250195485-A1 PROPIONIC ACID DERIVATIVE AND MEDICAL USE THEREOF XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) 2025-06-19 US disclosed
US-12221416-B2 Antagonists of human integrin α4β7 MORPHIC THERAPEUTIC, INC. (US) 2025-02-11 US disclosed
WO-2025026955-A1 NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS GALAPAGOS NV (BE) 2025-02-06 WO disclosed
US-20240294475-A1 ANTAGONISTS OF HUMAN INTEGRIN (ALPHA4)(BETA7) MORPHIC THERAPEUTIC, INC. 2024-09-05 US disclosed
CN-118591535-A Propionic acid derivative and application thereof in medicine 西藏海思科制药有限公司 2024-09-03 CN disclosed
CN-118354999-A Pyridazine-1 (6H) -6-oxo compound and preparation method and application thereof 深圳信立泰药业股份有限公司 2024-07-16 CN disclosed
US-11999732-B2 P2X3 receptor antagonists RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA SPA (IT) 2024-06-04 US disclosed
US-4596675-A Polypeptides MONSANTO COMPANY (US) 1986-06-24 US disclosed
US-4569907-A Thiopeptolide substrates for vertebrate collagenase MONSANTO COMPANY (US) 1986-02-11 US disclosed
WO-1985005362-A1 ORALLY ACTIVE HEPARIN MULTIPLETS BODOR NICHOLAS S 1985-12-05 WO disclosed
EP-0155981-A2 Derivatives of alkoxythiophenol; alkoxyphenolthio carbamates HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1985-10-02 EP disclosed
EP-0149593-A2 Novel thiopeptolide substrates for vertebrate collagenase Monsanto Company (US) 1985-07-24 EP disclosed
US-4528399-A Benzo[b]thiophenes intermediates HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1985-07-09 US disclosed
US-4436748-A HYPOTENSIVES, DIURETICS HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1984-03-13 US disclosed
US-4307232-A Preparation of dialkyl- and diarylphosphonoalkanoic acids and substituted acrylic acids E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-12-22 US disclosed
US-4199346-A Herbicides based on 2-dibenzofuranyloxyalkanecarboxylic acid derivatives AMERICAN HOECHST CORPORATION (US) 1980-04-22 US disclosed
US-3975432-A Process for preparing 2-(6-methoxy-2-naphthyl)propionic acid SYNTEX CORPORATION (PM) 1976-08-17 US disclosed