Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11502520 | 0.75 | MAPT (0.41) | GSTP1ALDH1A1MAPTHIF1A | |
| SCHEMBL5791186 | 0.72 | BRD4 (0.41) | BRD4ALDH1A1MAPTGAATSHR | |
| SCHEMBL9863913 | 0.70 | CHRNB4 (0.41) | ALDH1A1MAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL11466992 | 0.69 | BRD4 (0.46) | BRD4ALDH1A1MAPTTSHRKDM4E | |
| SCHEMBL277115 | 0.68 | GSTP1 (0.37) | GSTP1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL22780738 | 0.67 | ALDH1A1 (0.34) | ALDH1A1MAPTGAATSHRKDM4E | |
| SCHEMBL28272733 | 0.67 | PSMB5 (0.51) | PSMB5PSMB1 | |
| SCHEMBL745837 | 0.66 | — | — | |
| SCHEMBL1274254 | 0.64 | BRD4 (0.38) | BRD4ALDH1A1MAPTGAATSHR | |
| SCHEMBL8027778 | 0.63 | GSTP1 (0.46) | GSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900216-A1 | 1,3-OXAZIN-4-ONE DERIVATES AS HERBICIDES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION | RHONE-POULENC AGRICULTURE LTD. (GB) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997040041-A1 | 1,3-OXAZIN-4-ONE DERIVATES AS HERBICIDES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-10-30 | — | — | WO | disclosed |