Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.86 |
| ▸ | MAPT | P10636 | 6/20 | 0.86 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.86 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.86 |
| ▸ | MEN1 | O00255 | 5/20 | 0.86 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.86 |
| ▸ | MAOB | P27338 | 4/20 | 0.86 |
| ▸ | IP6K2 | Q9UHH9 | 4/20 | 0.86 |
| ▸ | FLT3 | P36888 | 4/20 | 0.86 |
| ▸ | NPC1 | O15118 | 4/20 | 0.86 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.86 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.86 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.86 |
| ▸ | MAOA | P21397 | 4/20 | 0.86 |
| ▸ | TP53 | P04637 | 3/20 | 0.86 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.86 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.86 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.86 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acacetin SCHEMBL29387049 | 0.93 | CYP1B1 (1.00) | CYP1B1MAPTCYP1A1CYP1A2MEN1 | |
| Acacetin SCHEMBL107712 | 0.93 | CYP1B1 (1.00) | CYP1B1MAPTCYP1A1CYP1A2MEN1 | |
| Acacetin SCHEMBL28278297 | 0.92 | CYP1B1 (0.97) | CYP1B1MAPTCYP1A1CYP1A2MEN1 | |
| Apigenin Dimethylether SCHEMBL1176691 | 0.88 | MAOB (1.00) | CYP1B1MAPTCYP1A1CYP1A2MEN1 | |
| Apigenin Dimethylether SCHEMBL29392759 | 0.88 | MAOB (1.00) | CYP1B1MAPTCYP1A1CYP1A2MEN1 | |
| SCHEMBL8429597 | 0.86 | XDH (0.70) | CYP1B1MAPTCYP1A1CYP1A2MEN1 | |
| SCHEMBL8308052 | 0.86 | MAOB (0.67) | CYP1B1MAPTCYP1A1CYP1A2MEN1 | |
| Acacetin SCHEMBL8304770 | 0.86 | CYP1B1 (0.86) | CYP1B1MAPTCYP1A1CYP1A2MEN1 | |
| SCHEMBL8305040 | 0.85 | MAPT (0.73) | CYP1B1MAPTCYP1A1CYP1A2MEN1 | |
| SCHEMBL8429204 | 0.83 | MAOB (0.62) | CYP1B1MAPTCYP1A1CYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709383-B1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-12-15 | — | — | EP | disclosed |
| EP-0709383-A1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-05-01 | — | — | EP | disclosed |