Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8311952 | 0.86 | LMNA (0.51) | MAPTLMNAPTGS2GAAKDM4E | |
| SCHEMBL12122655 | 0.86 | TSHR (0.60) | MAPTLMNAKDM4ETSHRALDH1A1 | |
| SCHEMBL14982241 | 0.85 | MAPT (0.56) | MAPTNPSR1LMNAGAAKDM4E | |
| SCHEMBL14982231 | 0.85 | MAPT (0.50) | MAPTNPSR1LMNAGAAKDM4E | |
| SCHEMBL14982229 | 0.80 | MAPT (0.44) | MAPTGAAKDM4ETSHRALDH1A1 | |
| SCHEMBL24039001 | 0.77 | KDM4E (0.49) | MAPTGAAKDM4ETSHRALDH1A1 | |
| SCHEMBL8310550 | 0.76 | PTGS2 (0.48) | MAPTPTGS2GAAMAPK1 | |
| SCHEMBL1160614 | 0.76 | TSHR (0.52) | LMNAKDM4ETSHRALDH1A1MAPK1 | |
| SCHEMBL14982223 | 0.74 | HTT (0.44) | MAPTLMNAGAAKDM4ETSHR | |
| SCHEMBL24638211 | 0.74 | MAPT (0.38) | MAPTLMNAGAAKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945437-A1 | Pyrazolyl acrylic acid- and pyrazolyl oximino-acetic acid derivatives, their preparation and their use as fungicides | SDS Biotech K.K. (JP) | 1999-09-29 | — | — | EP | disclosed |