Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | XPO1 | O14980 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8309601 | 0.76 | MAPT (0.52) | PTGS2MAPTGAAMAPK1 | |
| SCHEMBL3398387 | 0.74 | PTGS2 (0.53) | PTGS2MAPTPDE4BNPC1GAA | |
| SCHEMBL8311952 | 0.74 | LMNA (0.51) | PTGS2MAPTGAARAB9AKMO | |
| SCHEMBL13425935 | 0.71 | PTGS2 (0.47) | PTGS2MAPTXPO1PDE4BNPC1 | |
| SCHEMBL30130661 | 0.71 | FAAH (0.57) | MAPTXPO1TRPM8PDE4BNPC1 | |
| SCHEMBL14982231 | 0.69 | MAPT (0.50) | MAPTGAAMAPK1 | |
| SCHEMBL8624064 | 0.68 | PTGS2 (0.47) | PTGS2MAPTPDE4BNPC1GAA | |
| SCHEMBL16664794 | 0.68 | CTSS (0.44) | MAPTPDE4BGAA | |
| SCHEMBL8311450 | 0.68 | PTGS2 (0.44) | PTGS2MAPTXPO1PDE4BNPC1 | |
| SCHEMBL7248442 | 0.67 | ESR2 (0.51) | MAPTGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945437-A1 | Pyrazolyl acrylic acid- and pyrazolyl oximino-acetic acid derivatives, their preparation and their use as fungicides | SDS Biotech K.K. (JP) | 1999-09-29 | — | — | EP | disclosed |