Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPN | P05981 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.49 |
| ▸ | VCAM1 | P19320 | 9/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.40 |
| ▸ | GLRB | P48167 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8335793 | 0.86 | GAA (0.57) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL9119059 | 0.81 | MAPT (0.53) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL4397391 | 0.81 | HPN (0.53) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL9411884 | 0.80 | ALDH1A1 (0.56) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL9550709 | 0.79 | HPN (0.50) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL646924 | 0.79 | ALOX15 (0.63) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL8337417 | 0.78 | GAA (0.49) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL7703078 | 0.78 | POLB (0.48) | MAPTALOX15GAASMN1; SMN2KMT2A | |
| SCHEMBL8309677 | 0.77 | MAPT (0.49) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL7698636 | 0.77 | HPGD (0.48) | HPNMAPTALOX15SIRT5GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903346-A1 | SYDNONE IMINE DERIVATIVES | Chugai Seiyaku Kabushiki Kaisha (JP) | 1999-03-24 | — | — | EP | disclosed |