Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.50 |
| ▸ | DRD2 | P14416 | 8/20 | 0.47 |
| ▸ | HTR2A | P28223 | 5/20 | 0.46 |
| ▸ | HTR1A | P08908 | 4/20 | 0.46 |
| ▸ | DRD3 | P35462 | 3/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6585091 | 0.98 | HRH3 (0.49) | HRH3DRD2HTR2AHTR1ADRD3 | |
| SCHEMBL7508874 | 0.87 | SLC6A2 (0.48) | HRH3DRD2HTR2AHTR1ADRD3 | |
| SCHEMBL8308852 | 0.83 | DRD2 (0.54) | HRH3DRD2HTR2AHTR1ADRD3 | |
| SCHEMBL6583194 | 0.82 | DRD2 (0.60) | DRD2HTR2AHTR1ADRD3HTR2C | |
| SCHEMBL6584542 | 0.81 | DRD2 (0.56) | HRH3DRD2HTR2AHTR1ADRD3 | |
| SCHEMBL6071407 | 0.81 | HRH3 (0.71) | HRH3DRD2 | |
| SCHEMBL6582055 | 0.80 | DRD2 (0.57) | HRH3DRD2HTR2AHTR1ADRD3 | |
| SCHEMBL6586944 | 0.80 | MAOA (0.58) | DRD2HTR2AHTR1ADRD3HTR2C | |
| SCHEMBL6588774 | 0.80 | MAOA (0.67) | DRD2DRD3DRD4 | |
| Oxalic Acid SCHEMBL7518216 | 0.80 | DRD2 (0.44) | HRH3DRD2HTR2AHTR1ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957100-A1 | DIAMINE DERIVATIVES AND PHARMACEUTICAL CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 1999-11-17 | — | — | EP | disclosed |