Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.57 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.57 |
| ▸ | HPGDS | O60760 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14856185 | 0.78 | RAB9A (0.74) | HPGDSRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL15087626 | 0.78 | RAB9A (0.74) | HPGDSRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL4199832 | 0.77 | TAS1R3 (0.79) | TAS1R3TAS1R1RAB9ANPC1KDM4E | |
| SCHEMBL24470901 | 0.74 | GAA (0.58) | HPGDSRAB9ANPC1KDM4EGAA | |
| SCHEMBL14856272 | 0.74 | RAB9A (0.68) | HPGDSRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL15087631 | 0.74 | RAB9A (0.68) | HPGDSRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL29362997 | 0.73 | TAS1R3 (0.73) | TAS1R3TAS1R1KDM4EHSD17B10MEN1 | |
| SCHEMBL24522315 | 0.73 | TAS1R3 (0.73) | TAS1R3TAS1R1KDM4EHSD17B10MEN1 | |
| SCHEMBL10246958 | 0.73 | MEN1 (0.53) | TAS1R3TAS1R1MEN1KMT2AALDH1A1 | |
| SCHEMBL703306 | 0.73 | TAS1R3 (1.00) | TAS1R3TAS1R1KDM4EHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528337-B1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-10-20 | — | — | EP | disclosed |
| US-5296495-A | Antiallergens, antiinflammatory | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0528337-A1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |