⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8316475 | 0.85 | CYP26A1 (0.33) | — | |
| SCHEMBL8315203 | 0.84 | PDE9A (0.31) | — | |
| SCHEMBL8314759 | 0.84 | CYP26A1 (0.34) | — | |
| SCHEMBL8314615 | 0.82 | MAPT (0.33) | — | |
| SCHEMBL8310428 | 0.82 | F2RL3 (0.33) | — | |
| Water SCHEMBL8314845 | 0.81 | F2RL3 (0.32) | — | |
| SCHEMBL6599372 | 0.80 | — | — | |
| SCHEMBL8315855 | 0.78 | RAB9A (0.48) | — | |
| SCHEMBL5800338 | 0.73 | CYP26A1 (0.37) | — | |
| SCHEMBL8310707 | 0.73 | F2RL3 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528337-B1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-10-20 | — | — | EP | disclosed |
| EP-0528337-A1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |