Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 9/20 | 0.66 |
| ▸ | QDPR | P09417 | 3/20 | 0.66 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.66 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19998281 | 0.79 | HTR2C (0.66) | HTR2CQDPRSIGMAR1NAMPTHRH3 | |
| SCHEMBL531984 | 0.79 | SIGMAR1 (1.00) | HTR2CQDPRSIGMAR1HTR2AHTR6 | |
| SCHEMBL8380936 | 0.79 | QDPR (1.00) | HTR2CQDPRSIGMAR1NAMPT | |
| SCHEMBL1199051 | 0.79 | HTR2C (1.00) | HTR2CQDPRSIGMAR1NAMPTHRH3 | |
| SCHEMBL5603685 | 0.79 | HTR2C (0.66) | HTR2CQDPRSIGMAR1NAMPTHRH3 | |
| SCHEMBL4671168 | 0.79 | HTR2C (0.66) | HTR2CQDPRSIGMAR1HTR2AHTR6 | |
| SCHEMBL3899585 | 0.79 | SIGMAR1 (0.92) | HTR2CQDPRSIGMAR1NAMPTHTR2A | |
| SCHEMBL532892 | 0.79 | HTR2C (0.66) | HTR2CQDPRSIGMAR1HTR2AHTR6 | |
| SCHEMBL415545 | 0.78 | SIGMAR1 (1.00) | HTR2CQDPRSIGMAR1HTR2AHTR6 | |
| Hydrochloric Acid SCHEMBL25217174 | 0.78 | HTR2C (1.00) | HTR2CQDPRSIGMAR1HTR2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3241823-B1 | PYRROLE AMIDE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | HITGEN LTD (CN) | 2019-04-17 | — | — | EP | disclosed |
| WO-2004080460-A1 | SUBSTITUTED PIPERIDINES AS NOVEL MDM2-p53 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-09-23 | — | — | WO | disclosed |