Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.33 |
| ▸ | LOX | P28300 | 2/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.32 |
| ▸ | FEN1 | P39748 | 2/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 2/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8314841 | 0.80 | BLM (0.34) | BLMLOXL2LOXALOX5APFEN1 | |
| SCHEMBL8315527 | 0.77 | KMT2A (0.39) | HCRTR1HCRTR2TGFBR1 | |
| SCHEMBL6610030 | 0.76 | BLM (0.37) | BLMLOXL2LOXALOX5APFEN1 | |
| SCHEMBL6612907 | 0.75 | BLM (0.37) | BLMLOXL2LOXALOX5APFEN1 | |
| SCHEMBL8126836 | 0.74 | BLM (0.38) | BLMLOXL2LOXALOX5APFEN1 | |
| SCHEMBL6609150 | 0.74 | BLM (0.36) | BLMLOXL2LOXALOX5APFEN1 | |
| SCHEMBL6611166 | 0.74 | BLM (0.34) | BLMLOXL2LOXTGFBR1RXRA | |
| SCHEMBL8481697 | 0.73 | BLM (0.38) | BLMHDAC1HDAC6LOXL2LOX | |
| SCHEMBL8475227 | 0.73 | CYP11B1 (0.36) | BLMHDAC1HDAC6LOXL2LOX | |
| SCHEMBL6609586 | 0.72 | BLM (0.34) | BLMLOXL2LOXALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955292-A1 | Herbicidal 2-(cycloalk(en)yloxy)-6-(hetero)aryloxy(thio)pyridines | American Cyanamid Company (US) | 1999-11-10 | — | — | EP | claimed |
| EP-0946552-A1 | SULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1999-10-06 | — | — | EP | claimed |
| WO-1998013366-A1 | SULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1998-04-02 | — | — | WO | claimed |
| EP-0955292-A1 | Herbicidal 2-(cycloalk(en)yloxy)-6-(hetero)aryloxy(thio)pyridines | American Cyanamid Company (US) | 1999-11-10 | — | — | EP | disclosed |