Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 13/20 | 0.59 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.57 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14782824 | 1.00 | PTGES (0.59) | PTGESERCC1ERCC4TSHRAPEX1 | |
| SCHEMBL22060011 | 0.88 | NR1H4 (0.59) | PTGESERCC1ERCC4TSHRAPEX1 | |
| SCHEMBL14782792 | 0.86 | PTGES (0.57) | PTGESERCC1ERCC4TSHR | |
| SCHEMBL18810338 | 0.85 | PTGES (0.56) | PTGESERCC1ERCC4TSHR | |
| SCHEMBL8310378 | 0.84 | TSHR (0.66) | PTGESERCC1ERCC4TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL20489719 | 0.83 | PTGES (0.55) | PTGESERCC1ERCC4TSHR | |
| Hydrochloric Acid SCHEMBL29416936 | 0.83 | PTGES (0.55) | PTGESERCC1ERCC4TSHR | |
| SCHEMBL20149739 | 0.83 | KMT2A (0.56) | TSHRAPEX1NR1H4ALDH1A1TP53 | |
| SCHEMBL14782706 | 0.83 | HPGD (0.55) | PTGESTSHRAPEX1NR1H4ALDH1A1 | |
| SCHEMBL14816996 | 0.83 | ALDH1A1 (0.52) | TSHRAPEX1NR1H4ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114302874-B | Indole carboxamide derivatives and pharmaceutical compositions containing the same | 国际药品株式会社 | 2025-02-25 | — | — | CN | disclosed |
| EP-4023638-A1 | INDOLE CARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Kukje Pharma Co., Ltd. (KR) | 2022-07-06 | — | — | EP | disclosed |
| CN-114302874-A | Indole carboxamide derivatives and pharmaceutical compositions comprising same | 国际药品株式会社 | 2022-04-08 | — | — | CN | disclosed |