Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 7/20 | 0.35 |
| ▸ | THRA | P10827 | 6/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8307840 | 0.84 | MAPT (0.41) | HSD17B10TSHRALDH1A1KDM4E | |
| SCHEMBL8311738 | 0.82 | THRB (0.36) | HSD17B10TSHRTHRBTHRALCK | |
| SCHEMBL8310015 | 0.81 | ALDH1A1 (0.35) | HSD17B10TSHRLCKFYNALDH1A1 | |
| SCHEMBL8494455 | 0.80 | HSD17B10 (0.47) | HSD17B10TSHRLCKFYNALDH1A1 | |
| SCHEMBL8308298 | 0.80 | — | — | |
| SCHEMBL8310017 | 0.77 | HSD17B10 (0.35) | HSD17B10TSHRTHRBTHRALCK | |
| SCHEMBL8310598 | 0.77 | RAB9A (0.49) | ALDH1A1 | |
| SCHEMBL8391702 | 0.74 | LCK (0.40) | HSD17B10TSHRLCKFYNALDH1A1 | |
| SCHEMBL8309730 | 0.74 | — | — | |
| SCHEMBL8309731 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918056-A1 | Herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1999-05-26 | — | — | EP | disclosed |