Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL248949 | 0.91 | — | — | |
| Chloroform SCHEMBL8309128 | 0.83 | CYP4F2 (0.35) | CYP4F2CYP4A11 | |
| Chloroform SCHEMBL8311138 | 0.83 | PRKCA (0.40) | PRKCAPOLBGAANPSR1 | |
| Chloroform SCHEMBL8307756 | 0.74 | ALDH1A1 (0.34) | — | |
| SCHEMBL63686 | 0.72 | — | — | |
| Chloroform SCHEMBL8311625 | 0.71 | NPC1 (0.32) | — | |
| SCHEMBL10686206 | 0.71 | POLB (0.43) | PRKCACYP4F2CYP4A11POLBGAA | |
| SCHEMBL2179864 | 0.71 | CYP4F2 (0.39) | CYP4F2CYP4A11 | |
| SCHEMBL300 | 0.70 | — | — | |
| SCHEMBL6078202 | 0.70 | CYP4F2 (0.31) | CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5914339-A | ANTI-DIABETIC AND/OR ANTIHYPERGLYCEMIA AND/OR ANTI-OBESITY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-06-22 | — | — | US | disclosed |
| EP-0901484-A1 | SUBSTITUTED 1, 3-BENZODIOXOLES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997043273-A1 | SUBSTITUTED 1, 3-BENZODIOXOLES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-11-20 | — | — | WO | disclosed |