Sugi Predict

Sugi Predict / Compounds / Chloroform

Chloroform

Chloroform

SCHEMBL8307756

CC(C)(C)CC(=O)OCI.ClC(Cl)Cl

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 1/20 0.34
▸ LMNA P02545 1/20 0.34
▸ MIF P14174 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11058319 0.91 LMNA (0.34) ALDH1A1LMNAMIF
Chloroform SCHEMBL8309856 0.84 ALDH1A1 (0.33) ALDH1A1LMNA
Chloroform SCHEMBL8310481 0.74 PRKCA (0.42) —
Chloroform SCHEMBL8309854 0.73 — —
SCHEMBL697173 0.73 LMNA (0.37) ALDH1A1LMNAMIF
Chloroform SCHEMBL8308657 0.72 ALDH1A1 (0.46) ALDH1A1LMNA
SCHEMBL15694063 0.72 DGKA (0.39) ALDH1A1LMNAMIF
SCHEMBL2533392 0.71 LMNA (0.33) ALDH1A1LMNAMIF
Chloroform SCHEMBL8309128 0.71 CYP4F2 (0.35) —
SCHEMBL12028701 0.70 LMNA (0.35) ALDH1A1LMNAMIF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5914339-A ANTI-DIABETIC AND/OR ANTIHYPERGLYCEMIA AND/OR ANTI-OBESITY AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1999-06-22 — — US disclosed
EP-0901484-A1 SUBSTITUTED 1, 3-BENZODIOXOLES AMERICAN HOME PRODUCTS CORPORATION (US) 1999-03-17 — — EP disclosed
WO-1997043273-A1 SUBSTITUTED 1, 3-BENZODIOXOLES AMERICAN HOME PRODUCTS CORPORATION (US) 1997-11-20 — — WO disclosed