Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 12/20 | 0.43 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.38 |
| ▸ | SLC26A4 | O43511 | 2/20 | 0.37 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.35 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8311549 | 0.90 | PTGER4 (0.40) | PTGER4RAPGEF3SLC26A4 | |
| SCHEMBL8313568 | 0.87 | CYSLTR2 (0.42) | PTGER4RAPGEF3ALKBH2ALKBH3 | |
| SCHEMBL8310775 | 0.84 | MAOB (0.42) | SLC26A4KMT2A | |
| SCHEMBL8316517 | 0.84 | BCL2 (0.43) | PTGER4SLC26A4MEN1KMT2A | |
| SCHEMBL9400022 | 0.82 | PTPRG (0.40) | PTGER4ALKBH2ALKBH3MEN1KMT2A | |
| SCHEMBL210686 | 0.79 | PPARD (0.42) | PTGER4SLC26A4MEN1KMT2A | |
| SCHEMBL29623656 | 0.79 | PPARD (0.42) | PTGER4SLC26A4MEN1KMT2A | |
| SCHEMBL8784066 | 0.79 | PTGER4 (0.46) | PTGER4RAPGEF3SLC26A4MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1224090 | 0.78 | PPARD (0.41) | PTGER4SLC26A4MEN1KMT2A | |
| SCHEMBL6598204 | 0.78 | ALKBH2 (0.39) | PTGER4ALKBH2ALKBH3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528337-B1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-10-20 | — | — | EP | disclosed |
| US-5296495-A | Antiallergens, antiinflammatory | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0528337-A1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |