SCHEMBL8310679

SCHEMBL8310679

N#Cc1c(Br)ccc([N+](=O)[O-])c1C#N

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.41
VCAM1 P19320 4/20 0.40
BCHE P06276 1/20 0.37
ACHE P22303 1/20 0.37
CES1 P23141 1/20 0.37
ALDH1A1 P00352 4/20 0.37
HPGD P15428 2/20 0.37
CYP2D6 P10635 1/20 0.37
CTSB P07858 2/20 0.36
CYP3A4 P08684 3/20 0.35
EGFR P00533 1/20 0.35
KDM4E B2RXH2 1/20 0.35
LMNA P02545 1/20 0.35
CYP1A2 P05177 1/20 0.35
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35
CYP2C9 P11712 1/20 0.35
RECQL P46063 1/20 0.35
BLM P54132 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9575163 0.84 TDP1 (0.41) RAB9AVCAM1ALDH1A1CYP2D6CTSB
SCHEMBL4023385 0.83 TDP1 (0.45) VCAM1ALDH1A1HPGDCYP2D6CYP3A4
SCHEMBL8313813 0.77 VCAM1 (0.56) RAB9AVCAM1ALDH1A1HPGDMAPT
SCHEMBL9314849 0.77 TDP1 (0.42) RAB9AVCAM1ALDH1A1HPGDCTSB
SCHEMBL2416493 0.77 ATM (0.42) RAB9AVCAM1ALDH1A1HPGDCTSB
SCHEMBL27891587 0.76 L3MBTL1 (0.41) ALDH1A1HPGDCYP3A4KDM4ELMNA
SCHEMBL2656134 0.76 TSHR (0.48) RAB9AVCAM1ALDH1A1CTSBCYP3A4
SCHEMBL618153 0.75 TDP1 (0.54) RAB9AVCAM1ALDH1A1HPGDHSD17B10
SCHEMBL22445767 0.73 MEN1 (0.38) VCAM1ALDH1A1HPGDCYP3A4KDM4E
SCHEMBL21808044 0.73 ALDH1A1 (0.45) ALDH1A1CYP3A4EGFRKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0519423-B1 Phthalocyanine compounds and usage thereof MITSUI CHEMICALS INC (JP) 1999-03-03 EP disclosed
US-5695911-A CONTAINING PHTHALOCYANINE COMPOUND MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1997-12-09 US disclosed
US-5380842-A Color filters MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1995-01-10 US disclosed
EP-0519423-A2 Phthalocyanine compounds and usage thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-12-23 EP disclosed