Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7938078 | 0.83 | TRPA1 (0.54) | TRPA1ATMHSD17B10MAPTMAPK1 | |
| SCHEMBL9801566 | 0.82 | MAPT (0.46) | ATMIDO1HSD17B10MAPTMAPK1 | |
| SCHEMBL11406396 | 0.81 | TRPA1 (0.52) | TRPA1ATMHSD17B10MAPTMAPK1 | |
| SCHEMBL12582085 | 0.78 | IDO1 (0.50) | TRPA1ATMIDO1MAPTMAPK1 | |
| SCHEMBL17715571 | 0.78 | HPGD (0.52) | TRPA1ATMIDO1HSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL27722164 | 0.77 | TRPA1 (0.48) | TRPA1ATMHSD17B10MAPTMAPK1 | |
| SCHEMBL457878 | 0.77 | — | — | |
| SCHEMBL1952571 | 0.76 | IDO1 (0.43) | TRPA1ATMIDO1HSD17B10MAPT | |
| SCHEMBL4873527 | 0.76 | TRPA1 (0.72) | TRPA1ATMHSD17B10MAPTMAPK1 | |
| SCHEMBL33721 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115851025-A | Environment-tolerant intumescent epoxy fire-retardant coating and preparation method and application thereof | 长春理工大学 | 2023-03-28 | — | — | CN | claimed |
| CN-108219442-A | A kind of high polymer grouting material and preparation method thereof | 广东科技学院 | 2018-06-29 | — | — | CN | claimed |
| CN-1074312-C | Composite catalyst for tripolymerization of isocyanic ester | SHANXI COAL CHEM INST (CN) | 2001-11-07 | — | — | CN | claimed |
| CN-1216263-A | Composite catalyst for tripolymerization of isocyanic ester | SHANXI COAL CHEM INST (CN) | 1999-05-12 | — | — | CN | claimed |
| CN-1026490-C | Composite of high-temp. modified polyisocyanurate | INST OF CONSTRUCTION TECHNOLOG (CN) | 1994-11-09 | — | — | CN | claimed |
| CN-1041371-A | The constituent of heat resist modification poly-isocyanurate | INST OF CONSTRUCTION TECHNOLOG (CN) | 1990-04-18 | — | — | CN | claimed |
| EP-3268372-B9 | KV1.3 INHIBITORS AND THEIR MEDICAL APPLICATION | 4SC AG (DE) | 2021-03-31 | — | — | EP | disclosed |
| CN-107548397-B | Kv1.3 inhibitors and medical uses thereof | 4SC股份公司 | 2020-12-29 | — | — | CN | disclosed |
| US-20200377514-A1 | KV1.3 INHIBITORS AND THEIR MEDICAL APPLICATION | 4SC AG (DE) | 2020-12-03 | — | — | US | disclosed |
| EP-3344997-B1 | OPIOID RECEPTOR MODULATORS AND USE THEREOF | UNIV MINNESOTA (US) | 2020-11-18 | — | — | EP | disclosed |
| US-10822345-B2 | KV1.3 inhibitors and their medical application | 4SC AG (DE) | 2020-11-03 | — | — | US | disclosed |
| US-20200339592-A1 | KV1.3 INHIBITORS AND THEIR MEDICAL APPLICATION | 4SC AG (DE) | 2020-10-29 | — | — | US | disclosed |
| US-10723743-B2 | Kv1.3 inhibitors and their medical application | 4SC AG (DE) | 2020-07-28 | — | — | US | disclosed |
| CN-1216263-A | Composite catalyst for tripolymerization of isocyanic ester | SHANXI COAL CHEM INST (CN) | 1999-05-12 | — | — | CN | disclosed |
| CN-1216263-A | Composite catalyst for tripolymerization of isocyanic ester | SHANXI COAL CHEM INST (CN) | 1999-05-12 | — | — | CN | disclosed |
| CN-1026490-C | Composite of high-temp. modified polyisocyanurate | INST OF CONSTRUCTION TECHNOLOG (CN) | 1994-11-09 | — | — | CN | disclosed |
| CN-1041371-A | The constituent of heat resist modification poly-isocyanurate | INST OF CONSTRUCTION TECHNOLOG (CN) | 1990-04-18 | — | — | CN | disclosed |
| CN-1041371-A | The constituent of heat resist modification poly-isocyanurate | INST OF CONSTRUCTION TECHNOLOG (CN) | 1990-04-18 | — | — | CN | disclosed |
| US-4855427-A | Epoxy resins obtained from reaction of epoxyalkyl halides and aromatic hydroxyl-containing melamines | BASF AKTIENGESELLSCHAFT (DE) | 1989-08-08 | — | — | US | disclosed |
| EP-0296493-A2 | Epoxy resins | BASF Aktiengesellschaft (DE) | 1988-12-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200339592-A1 | KV1.3 INHIBITORS AND THEIR MEDICAL APPLICATION | KCNA3, KCNN3, KCNK3 | TRPA1 157/4885ATM 3030/4885IDO1 3389/4885 |
| US-10723743-B2 | Kv1.3 inhibitors and their medical application | KCNA3, KCNN3, KCNK3 | TRPA1 157/4885ATM 3030/4885IDO1 3389/4885 |
| US-10822345-B2 | KV1.3 inhibitors and their medical application | KCNA3, KCNN3, KCNK3 | TRPA1 157/4885ATM 3030/4885IDO1 3389/4885 |
| US-20200377514-A1 | KV1.3 INHIBITORS AND THEIR MEDICAL APPLICATION | KCNN3, KCNN2, KCNA3 | TRPA1 134/4885ATM 3163/4885IDO1 3426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.