Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22779822 | 0.86 | MAPT (0.47) | MAPTALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL1548708 | 0.86 | KEAP1 (0.54) | MAPTALDH1A1TDP1HSD17B10MAPK1 | |
| Hydrochloric Acid SCHEMBL2871283 | 0.84 | KEAP1 (0.52) | MAPTALDH1A1TDP1HSD17B10MAPK1 | |
| SCHEMBL9232217 | 0.82 | MAPT (0.53) | MAPTALDH1A1KDM4EPOLBUSP2 | |
| SCHEMBL30368237 | 0.82 | MAPT (0.53) | MAPTALDH1A1KDM4EPOLBUSP2 | |
| SCHEMBL8310698 | 0.82 | TRPA1 (0.52) | MAPTALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL14857685 | 0.82 | ALDH1A1 (0.39) | MAPTALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL19277812 | 0.82 | MAPT (0.38) | MAPTALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL9230273 | 0.82 | ALDH1A1 (0.49) | MAPTALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL14861504 | 0.82 | ALDH1A1 (0.39) | MAPTALDH1A1TDP1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071947-A | Polymerization of a bismaleimide and an aromatic secondary diamine in the presence of dicumyl peroxide and imidazole mixed catalyst | LUCKY, LTD. (KR) | 1991-12-10 | — | — | US | claimed |
| WO-2020011246-A1 | BENZENE RING-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 广州丹康医药生物有限公司 | 2020-01-16 | — | — | WO | disclosed |
| US-7777063-B2 | Organosilicon compounds their preparation and their use | EVONIK DEGUSSA GMBH (DE) | 2010-08-17 | — | — | US | disclosed |
| US-7777063-B2 | Organosilicon compounds their preparation and their use | EVONIK DEGUSSA GMBH (DE) | 2010-08-17 | — | — | US | disclosed |
| US-20080275152-A1 | Halogen-free, flame-retardant polyurethane foams | LANXESS DEUTSCHLAND GMBH | 2008-11-06 | — | — | US | disclosed |
| US-20080275152-A1 | Halogen-free, flame-retardant polyurethane foams | LANXESS DEUTSCHLAND GMBH | 2008-11-06 | — | — | US | disclosed |
| EP-1964880-A1 | Halogen-free flame-resistant polyurethane foams | Lanxess Deutschland GmbH (DE) | 2008-09-03 | — | — | EP | disclosed |
| US-20070066760-A1 | Organosilicon compounds their preparation and their use | DEGUSSA AG (DE) | 2007-03-22 | — | — | US | disclosed |
| US-20070066760-A1 | Organosilicon compounds their preparation and their use | DEGUSSA AG (DE) | 2007-03-22 | — | — | US | disclosed |
| US-5071947-A | Polymerization of a bismaleimide and an aromatic secondary diamine in the presence of dicumyl peroxide and imidazole mixed catalyst | LUCKY, LTD. (KR) | 1991-12-10 | — | — | US | disclosed |
| US-5004774-A | Heat resistance, shrinkage inhibition | LUCKY, LTD. (KR) | 1991-04-02 | — | — | US | disclosed |
| US-3943158-A | POLYURETHANE MONOMERS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066760-A1 | Organosilicon compounds their preparation and their use | MSH6, MCM6, SI | MAPT 1545/4885ALDH1A1 1519/4885TDP1 1740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.