Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 2/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8312946 | 0.79 | CYP4F2 (0.39) | HTT | |
| SCHEMBL8310764 | 0.76 | PARP15 (0.45) | GRM2HPGDPARP10HTT | |
| SCHEMBL8310766 | 0.76 | PARP15 (0.45) | GRM2HPGDPARP10HTT | |
| SCHEMBL8315754 | 0.75 | FFAR1 (0.48) | GRM2DDB1CRBNPARP10HTT | |
| SCHEMBL8314917 | 0.74 | MAPT (0.58) | HPGDALDH1A1TSHR | |
| SCHEMBL7217161 | 0.74 | MAPT (0.49) | DDB1CRBNALDH1A1TSHR | |
| SCHEMBL8181635 | 0.74 | CA2 (0.41) | — | |
| SCHEMBL8957454 | 0.73 | FFAR1 (0.38) | ALDH1A1HTT | |
| SCHEMBL8189509 | 0.73 | GAA (0.53) | NAAAALDH1A1HTT | |
| SCHEMBL12521895 | 0.73 | CTSK (0.46) | PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0597102-B1 | NOVEL BISHETEROCYCLIC DERIVATIVE OR SALT THEREOF AND HYPOGLYCEMIC COMPOSITION | YAMANOUCHI PHARMA CO LTD (JP) | 1999-01-07 | — | — | EP | claimed |
| EP-0597102-A1 | NOVEL BISHETEROCYCLIC DERIVATIVE OR SALT THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1994-05-18 | — | — | EP | claimed |
| EP-0597102-B1 | NOVEL BISHETEROCYCLIC DERIVATIVE OR SALT THEREOF AND HYPOGLYCEMIC COMPOSITION | YAMANOUCHI PHARMA CO LTD (JP) | 1999-01-07 | — | — | EP | disclosed |
| US-5508296-A | HYPOGLYCEMIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1996-04-16 | — | — | US | disclosed |
| EP-0597102-A1 | NOVEL BISHETEROCYCLIC DERIVATIVE OR SALT THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1994-05-18 | — | — | EP | disclosed |