Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8181635 | 0.94 | CA2 (0.41) | CA2FFAR1PPARGKMT2ABRD4 | |
| SCHEMBL8315528 | 0.91 | CA2 (0.37) | CYP4F2CYP4A11CA2FFAR1HTT | |
| SCHEMBL8957454 | 0.90 | FFAR1 (0.38) | CYP4F2CYP4A11CA2FFAR1HTT | |
| SCHEMBL8315754 | 0.86 | FFAR1 (0.48) | CYP4F2CYP4A11FFAR1HTTPPARG | |
| SCHEMBL1385865 | 0.83 | ITGB3 (0.45) | KMT2AMEN1 | |
| SCHEMBL8189509 | 0.83 | GAA (0.53) | CYP4F2CYP4A11HTTPPARGKMT2A | |
| SCHEMBL12521895 | 0.83 | CTSK (0.46) | CYP4F2CYP4A11CA2FFAR1GLA | |
| SCHEMBL11262445 | 0.81 | MDM2 (0.44) | CA2PPARGPOLBDAO | |
| SCHEMBL7217161 | 0.81 | MAPT (0.49) | CYP4F2CYP4A11CA2BRD4 | |
| SCHEMBL7987893 | 0.81 | CAPN1 (0.41) | CA2GAADAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0597102-B1 | NOVEL BISHETEROCYCLIC DERIVATIVE OR SALT THEREOF AND HYPOGLYCEMIC COMPOSITION | YAMANOUCHI PHARMA CO LTD (JP) | 1999-01-07 | — | — | EP | disclosed |
| US-5508296-A | HYPOGLYCEMIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1996-04-16 | — | — | US | disclosed |
| EP-0597102-A1 | NOVEL BISHETEROCYCLIC DERIVATIVE OR SALT THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1994-05-18 | — | — | EP | disclosed |