Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 5/20 | 0.43 |
| ▸ | PARP1 | P09874 | 5/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 5/20 | 0.43 |
| ▸ | WNT3A | P56704 | 3/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 4/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.35 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.35 |
| ▸ | AXIN2 | Q9Y2T1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8310827 | 0.84 | PIK3CD (0.40) | NPC1ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL8316989 | 0.82 | PTGDR2 (0.38) | NISCHGAANPC1ALDH1A1KMT2A | |
| SCHEMBL8315862 | 0.82 | ALOX5 (0.44) | NISCHGAANPC1ALDH1A1MAPT | |
| SCHEMBL8312319 | 0.81 | NPC1 (0.37) | NISCHGAANPC1ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL8315893 | 0.81 | MAPT (0.38) | GAANPC1ALDH1A1BRD4MAPT | |
| SCHEMBL8315464 | 0.80 | PDE4B (0.39) | MAPT | |
| Hydrochloric Acid SCHEMBL8316299 | 0.80 | LOXL2 (0.39) | LTA4H | |
| SCHEMBL8311457 | 0.78 | APP (0.43) | GAANPC1ALDH1A1MEN1MAPT | |
| Hydrochloric Acid SCHEMBL8312117 | 0.77 | RAB9A (0.42) | NISCHNPC1ALDH1A1MEN1MAPT | |
| Hydrochloric Acid SCHEMBL8317268 | 0.77 | APP (0.42) | GAAMEN1MAPTKMT2AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0351856-B1 | Thiazolo[5,4-b]azepine compounds | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-09-15 | — | — | EP | disclosed |
| US-5300639-A | 2-oxo-3-carbonylamino-substituted azepine intermediates; lipoperoxide formation inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-04-05 | — | — | US | disclosed |
| US-5118806-A | Enzyme inhibitor for lipoxygenase; useful for treating cancer, hepatic diseases, inflammation, cerebrovascular diseases | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-06-02 | — | — | US | disclosed |
| US-4956360-A | LIPOPEROXIDE INHIBITORS, ENZYME INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-09-11 | — | — | US | disclosed |